I saw this paper at random: The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may […]

I am watching Brian Boutwell’s (Twitter, RG) talk at a recent conference and this got me thinking. What are we measuring? As far as I know, there are typically two outcome variables used in criminological studies: Official records convictions. Self-reported criminal or anti-social behavior. But exactly what trait are we trying to measure? It seems […]

Normally, testing colorism or other causal models of why human racial traits have nonzero relationships to socioeconomic outcomes requires that one has the following data: Measure of racial ancestry Measures of racial appearance Measures of socioeconomic outcomes such as income or educational attainment Path model wise, one can think of it this way: Discrimination models […]

I forgot to post this blog post at the time of publication as I usually do. However, here it is. As explored in some previous posts, John Fuerst and I have spent about 1.25 years (!) producing a massive article: published version runs 119 pages; 25k words without the references; 159k characters incl. spaces. We […]

In the comments on this SlateStarCodex post, someone is questioning my claim that sharing the chorion (what is that?) is unimportant: Emil: Uterine environment stuff is not important. We know this because of this study link.springer.com/article/10.1007/s10519-015-9745-3 and because ordinary siblings are about as similar as DZ twins who did share the uterus at the same […]

Non-Shared Environment Doesn’t Just Mean Schools And Peers Scott Alexander has a new post out summarizing the interpretations of what constitutes non-shared environment in the ACE model estimates from standard (MZ-DZ) twin studies. I’m happy that he wrote that up because I had been thinking of writing up the same points, but he is a […]

Medical researchers have noticed that some diseases differ by SIRE (self-identified race/ethnicity) groups which differ by genomic (racial) ancestry. Hence, when genomic measures became available (last 15 years or so), they measured peoples relative proportions of ancestry in mixed populations to see if the diseases would be predictable by ancestry. They were. This establishes with […]

Comment on: infoproc.blogspot.dk/2016/02/missing-heritability-and-gcta-update-on.html First, skim this paper: journals.plos.org/ploso… Genomic prediction works fairly well. This recent paper does a cross-data cross-method analysis of genomic prediction methods using 10 fold cross-validation to account for overfitting. In general, the compressed sensing/lasso/regularization methods perform well, but surprisingly an even simpler method comes out on top (mRMR): Maximum Relevancy Minimum […]

Link: www.gwern.net/Embryo%20selection Embryo selection an add-on to IVF [his summary]: harvest x eggs fertilize them and create x embryos culture the embryos to either cleavage (2-4 days) or blastocyst (5-6 days) stage; of them, y will still be alive & not grossly abnormal freeze the embryos optional: embryo selection using quality and PGS unfreeze & […]

Apparently, only a few studies have examined this question and they are not easily available. Because we obtained these, it makes sense to share our results. The datafile is on Google Drive. We will fill in more results as we find them. So far results reveal nothing surprising: MZ correlations are larger than DZ correlations. […]