Woodley reminded me of the dysgenics for health outcomes by linking me to a study about the increasing rates of cancer. I had first reached this conclusion back in 2005 when I realized what it means for evolution that we essentially keep almost everyone alive despite their genetic defects. The problem is quite simple: mutations […]

There’s a highly interesting new paper out: The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities (Mendelians are also known as monogenic disorders because they are inherited in patterns that follow Mendel’s laws.) Abstract: Discovering the genetic basis of a Mendelian phenotype establishes a causal link between genotype and phenotype, making possible carrier and […]

I oppose coercive eugenic policies, so don’t try to quote mine my blunt discussion as support for such policies. Hollywood has a new anti-eugenics movie out, called The Thinning. There’s a trailer, and it will likely spoil the entire movie for you, but I reckon it will be crappy anyway, so: For those too lazy […]

www.gwern.net/Embryo%20selection#counteracting-dysgenics Gwern has a very long and detailed post/page on embryo selection and related matters. You should definitely read it. He has just added a new section on counteracting dysgenics — the genetic evolution of undesirable traits — and asked for my comments/thoughts. The background for the discussion are the recent genomic findings supporting dysgenic […]

Quoted from Textbook of Human Reproductive Genetics, chapter 13: PGD within the“autonomy model” According to what may be called the “autonomy model,” prospective parents are free to use PGD in order to select embryos on the basis of any characteristic they prefer, whether health related or not. Opponents argue that selecting for non-medical characteristics violates […]

There seem to be ways to post knitr documents to WordPress blogs, but until that’s set up, I will be publishing them over at RPubs and posting a link here. The post begins like this: In a post published on his website, Gwern investigates the efficiency of embryo selection. It’s impressive work. In a later […]