Admixture mapping assisted GWAS

Medical researchers have noticed that some diseases differ by SIRE (self-identified race/ethnicity) groups which differ by genomic (racial) ancestry. Hence, when genomic measures became available (last 15 years or so), they measured peoples relative proportions of ancestry in mixed populations to see if the diseases would be predictable by ancestry. They were. This establishes with…

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Polygenic scores, genetic engineering, validity of GWAS results across major racial groups and the Piffer method

A PDF of this paper without formatting errors can be downloaded here. Abstract I review recent findings in human behavioral genetics and their implications for selective breeding and estimation of genotypic racial differences in polygenic traits. Key words: behavioral genetics, cognitive ability, GWAS, intelligence, IQ, race, selective breeding, embryo selection, genetic engineering, educational attainment 1….

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William Shockley, verbal tilt and interpersonal sensitivity

I recently read the biography of William Shockley. Basically, I am reading biographies of prominent researchers to gain an understanding of them. I was also thinking of writing one about Arthur Jensen, having already set up a website for him and read most of his writings and writings about him. www.goodreads.com/book/show/537597.Broken_Genius The book is written…

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Review of Metapedia’s Race and Intelligence review

Wikipedian battlegrounds For those who don’t know, Wikipedia is a common battleground for the ideological part of the race and intelligence debate. One can see this in the talk pages of these articles. See also the discussion of the phenomenon here. The most active pushers of environment-only right now are WeijiBaikeBianji and maunus. WBB got…

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Polygenic scores, genetic engineering, validity of GWAS results across major racial groups and the Piffer method

Abstract I review recent findings in human behavioral genetics and their implications for selective breeding and estimation of genotypic racial differences in polygenic traits. 1. Polygenic scores from all SNPs vs. p<α SNPs A recent paper (1) used polygenic scores derived from the Rietveld results (2) to score a non-overlapping sample of European Americans (EA)…

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SNPs within and between populations

A recent paper informs us that we have now found a small number of SNPs that explain skin color in European samples. In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional…

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An S factor among census tracts of Boston

Abstract A factor analysis was carried out on 6 socioeconomic variables for 506 census tracts of Boston. An S factor was found with positive loadings for median value of owner-occupied homes and average number of rooms in these; negative loadings for crime rate, pupil-teacher ratio, NOx pollution, and the proportion of the population of ‘lower…

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The sibling control design

A friend of mine and his brother just received their 23andme results. In a table they look like this (I have added myself for comparison): Macrorace Bro1 Bro2 Emil European 52.6 53 99.8 MENA 42.5 41.3 0.2 South Asian 2.8 3.4 0 East Asian & Amerindian 1.1 0.7 0 Sub-Saharan African 0.5 0.5 0 Oceanian…

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The general brain factor, working memory, parental income and education, and racial admixture

UNFINISHED ANALYSIS. POSTED HERE TO ESTABLISH PRIORITY. MORE TO FOLLOW! Updated 2015-12-04 Remains to be done: Admixture analysis (doing) Proofreading and editing Deciding how to control for age and scanner (technical question) Abstract I explore a large (N≈1000), open dataset of brain measurements and find a general factor of brain size (GBSF) that covers all…

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Examining the S factor in US states

Abstract A dataset of 25 diverse socioeconomic indicators for US states was compiled and subjected to factor analysis. Results showed that Washington DC was a strong outlier, but if it is excluded, then the S factor correlated strongly with state IQ (based on NAEP) at .75. Ethnoracial demographics of the states were related to the…

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