You can’t ignore gene-environment correlations when looking for gene-environment interactions

Humans love interactions, they tell interesting stories (however, no study has investigated this bias, AFAIK). However, statistics and nature hate interactions. Interactions in general have low prior, and because people fail to realize this properly, reports of interactions generally fail to replicate. This is also true for gene-environment interactions (GxE), the love-child of any would…

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Cognitive ability, surveys and measurement error: possible bias in GxE studies

I saw this paper at random: The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may…

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