FAQ for Dunkel et al 2019 Ashkenazim polygenic score for intelligence

Dunkel, C. S., Woodley of Menie, M. A., Pallesen, J., & Kirkegaard, E. O. (2019). Polygenic scores mediate the Jewish phenotypic advantage in educational attainment and cognitive ability compared with Catholics and Lutherans. Evolutionary Behavioral Sciences. So predictably, our study on Jewish IQ has elicited some rather harsh (and in some cases moralistic) criticisms from…

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Q/A with Antonio Regalado for genomics

Antonio Regalado is providing us with a recent series of the arguably best informed (compared to Guardian, Nature news etc.) popular science articles on genomics and its relevance to modern eugenics (embryo selection or genetic engineering) as well as the group differences causation question. www.technologyreview.com/s/609204/eugenics-20-were-at-the-dawn-of-choosing-embryos-by-health-height-and-more/ www.technologyreview.com/s/610251/forecasts-of-genetic-fate-just-got-a-lot-more-accurate/ www.technologyreview.com/s/610339/dna-tests-for-iq-are-coming-but-it-might-not-be-smart-to-take-one/ As background for some of these, I had…

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On the validity of polygenic scores, in general and in Africans

(See 2015 post) There’s a very interesting new preprint out: Heterogeneity in polygenic scores for common human traits Erin B Ware, Lauren L Schmitz, Jessica D Faul, Arianna Gard, Colter Mitchell, Jennifer A Smith, Wei Zhao, David Weir, Sharon LR Kardia bioRxiv 106062; doi: doi.org/10.1101/106062 This study investigates the creation of polygenic scores (PGS)s for…

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