Estimating the polygenicity of traits: an update
Readers will perhaps recall that I tried to come up with some metrics for the polygenicity of a trait back in 2016. Well, there's a new preprint now: Estimation of…
Metrics for quantifying genetic cardinality of a trait
It is common to talk about traits being monogenic or polygenic. We say that Sickle-cell disease is monogenic because its heritable variation among humans can be accounted for by a…